IL1RA antagonist Antibody (NBP1-43930)(0.1mg)

Catalog number: NBP1-43930
Price: Ask price from support chat or by Email
Product name: IL1RA antagonist Antibody (NBP1-43930)(0.1mg)

Applications

FACS
Uses:

The fluorochrome-conjugated CRM17 antibody has been tested by intracellular staining and flow cytometric analysis of LPS-activated, fixed/permeabilized human peripheral blood mononuclear cells. It is offered in 2 formats:

- μg size: This can be used at at less than or equal to 0.5 ug per test. A test is defined as the amount (μg)/test of antibody that will stain a cell sample in a final volume of 100 �L. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

- test size: has been pre-titrated and tested. This can be used at test size: 5 μl (0.25 μg)/per test The pre-titrated test size contains 0.2% BSA.

Dilutions: flow cytometry / FACS analysis

Background

The CRM17 antibody reacts with human interleukin-1 receptor antagonist (IL-1RA). IL-1RA is produced by macrophages, monocytes, neutrophils, synovial and dermal fibroblasts. The 17 kDa soluble form of IL-1RA (sIL-1RA) is produced by hepatocytes. IL-1RA inhibits the release of both forms of IL-1, the secretion of IL-2, and the expression of IL-2 receptors on the cell surface. IL-1RA also blocks the stimulation of prostaglandin E2 synthesis in synovial cells and the proliferation of thymocytes.

Details

Immunogen: The immunogen for this antibody was Fluorescein IL1RA.
Clone: CRM17
Isotype: IgG1

Notes

Packaging

Storage: Store at 4C. Do not freeze.
Buffer: Phosphate buffer pH 7.2,
Preservative: 0.09% Sodium Azide
Unit Size: 0.1mg (also available: , )
Limitations: This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Publications

Species

Human
Reactivity: This antibody is reactive to Human..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Summary

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Summary:

Teste

FACS
Uses:

The fluorochrome-conjugated CRM17 antibody has been tested by intracellular staining and flow cytometric analysis of LPS-activated, fixed/permeabilized human peripheral blood mononuclear cells. It is offered in 2 formats:

- μg size: This can be used at at less than or equal to 0.5 ug per test. A test is defined as the amount (μg)/test of antibody that will stain a cell sample in a final volume of 100 �L. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

- test size: has been pre-titrated and tested. This can be used at test size: 5 μl (0.25 μg)/per test The pre-titrated test size contains 0.2% BSA.

Dilutions: flow cytometry / FACS analysis