BRD3 Antibody (H00008019-M01)(0.1mg)

Catalog number: H00008019-M01
Price: Ask price from support chat or by Email
Product name: BRD3 Antibody (H00008019-M01)(0.1mg)

Applications

WB, IHC-P, ELISA
Uses: Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.
Dilutions: ELISA, Immunohistochemistry-Paraffin, Western Blot 1:500

Background

The bromodomain is a conserved 110 amino acid motif which specifically interacts with acetyl lysines, at least in the context of short histone H3 and H4 peptides. Although bromodomains have now been found in more than 40 different proteins, the function of this motif is poorly understood. The association of two N terminal bromodomains with a C terminal extraterminal (ET) domain defines the Fsh/Brd subgroup, which includes members in many species. In vertebrates, four members of the Fsh/Brd subgroup have now been identified: Brd2/RING3/fsrg1, Brd3/ORFX/fsrg2, Brd4/HUNK1/MCAP, and Brd5/BRDT. The Brd3/ORFX gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.

Details

Immunogen: BRD3 (AAH32124, 418 a.a. ~ 556 a.a) partial recombinant protein with GST tag.
Epitope: EPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRDHFLTCGV
Clone: 6E7
Isotype: IgG1 Kappa
Localization: Nuclear

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Packaging

Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer: Phosphate buffered saline, pH 7.2
Preservative: No Preservative
Limitations: This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Publications

Species

Human
Reactivity: Human. Other species not tested..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Summary

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Summary:

Teste

WB, IHC-P, ELISA
Uses: Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.
Dilutions: ELISA, Immunohistochemistry-Paraffin, Western Blot 1:500