Renal Cell Carcinoma (gp200) Antibody (NBP1-43792)(100tests)

Catalog number: NBP1-43792-100tests
Price: Ask price from support chat or by Email
Product name: Renal Cell Carcinoma (gp200) Antibody (NBP1-43792)(100tests)

Applications

FACS
Uses:

This MG38 antibody has been pre-titrated and tested by flow cytometric analysis of in vitro derived human dendritic cells and peripheral blood leukocytes. This can be used at 20 μl (0.06 μg)/per test. A test is defined as the amount (μg)/test of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 105 to 108 cells/test.

Dilutions: flow cytometry / FACS analysis

Background

The MG38 monoclonal antibody reacts with human CD205, also known as DEC-205, an integral membrane protein homologous to the macrophage mannose receptor. CD205 is an endocytic dendritic receptor that mediates efficient processing and presentation of antigens on MHC class II productions in vivo. CD205 is highly expressed by dendritic cells (DCs) within the T cell areas of lymphoid tissues, particularly on CD8+ DCs that are believed to play a role in cross-priming. Expression of CD205 is detected with this antibody at high intensity on in vitro derived mature human DCs (mDC) and at intermediate intensity on immature human DCs (iDC). All leukocytes from peripheral blood show a degree of staining with this mAb that can be minimized by using very low concentrations of MG38.

Details

Immunogen: The immunogen for this antibody was CD205.
Clone: MG38
Isotype: IgG2b Kappa

Notes

Packaging

Storage: Store at 4C. Do not freeze.
Buffer: Phosphate buffer pH 7.2,
Preservative: 0.09% Sodium Azide
Unit Size: 100tests (also available: )
Limitations: This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Publications

Species

Human
Reactivity: This antibody is reactive to Human..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Summary

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Summary:

Teste

FACS
Uses:

This MG38 antibody has been pre-titrated and tested by flow cytometric analysis of in vitro derived human dendritic cells and peripheral blood leukocytes. This can be used at 20 μl (0.06 μg)/per test. A test is defined as the amount (μg)/test of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 105 to 108 cells/test.

Dilutions: flow cytometry / FACS analysis