Prostate Specific Antigen Antibody (NB110-7920)(0.2mg)

Catalog number: NB110-7920
Price: Ask price from support chat or by Email
Product name: Prostate Specific Antigen Antibody (NB110-7920)(0.2mg)

Applications

ELISA
Uses: ELISASpecificity in ELISA - equimolar total PSA, epitope 3. Detection of PSA antigen: use as an antibody pair with NB120-10185. For the detection of free PSA: use as an antibody pair with NB120-10187.
Dilutions: ELISA assay dependent

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.

Details

Immunogen: Human PSA antigen purified from semenal plasma.
Clone: 2H9
Isotype: IgG2a
Localization: Cytoplasmic and Secreted

Notes

Packaging

Storage: Store at 4C. Do not freeze.
Buffer: PBS pH 7.4
Preservative: 0.1% Sodium Azide
Concentration: 3.0 mg/ml
Limitations: This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Publications

Species

Human
Reactivity: Cross-reacts with Human..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Summary

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Summary:

Teste

ELISA
Uses: ELISASpecificity in ELISA - equimolar total PSA, epitope 3. Detection of PSA antigen: use as an antibody pair with NB120-10185. For the detection of free PSA: use as an antibody pair with NB120-10187.
Dilutions: ELISA assay dependent