TIM-1 Antibody (NBP1-43540)(0.5mg)

Catalog number: NBP1-43540-05mg
Price: Ask price from support chat or by Email
Product name: TIM-1 Antibody (NBP1-43540)(0.5mg)

Applications

FACS
Uses:

This RMT1-10 antibody has been tested by flow cytometric analysis of mouse TIM-1 transfected cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Dilutions: flow cytometry / FACS analysis

Background

The RMT1-10 monoclonal antibody reacts with mouse TIM-1, a member of newly identified T cell immunoglobulin domain, mucin-like domain (TIM) gene family. RMT1-10 reacts with TIM-1 from C57Bl/6 mouse. RMT1-4, another antibody specific for TIM-1, reacts with the TIM-1 protein from both BALB/c and C57Bl/6 strains. TIM family of proteins are transmembrane proteins expressed by CD4 T cells. Recent studies demonstrate that the TIM family, particularly TIM-1, plays a critical role in immune responses that regulate the development of atopic diseases. Human TIM-1 is a functional receptor for hepatitis A virus (HAV). In humans, certain polymorphic variants of TIM-1 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV). Activation of T cells through TIM-1 by HAV or by its natural ligand may affect T cell differentiation and the development of Th2-driven allergic inflammatory responses.

Details

Immunogen: The immunogen for this antibody was TIM1.
Conjugate: Biotin
Clone: RMT1-10
Isotype: IgG2a Kappa

Notes

Packaging

Storage: Store at 4C. Do not freeze.
Buffer: Phosphate buffer pH 7.2,
Preservative: 0.09% Sodium Azide
Unit Size: 0.5mg (also available: , )
Limitations: This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Publications

Species

Mouse
Reactivity: This antibody is reactive to Mouse..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Summary

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Summary:

Teste

FACS
Uses:

This RMT1-10 antibody has been tested by flow cytometric analysis of mouse TIM-1 transfected cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Dilutions: flow cytometry / FACS analysis